Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548515 | 0.95 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21313305 | 0.95 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL9853352 | 0.95 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL5025146 | 0.92 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21084614 | 0.91 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28033748 | 0.91 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28328305 | 0.91 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| 1,1-Dichloroethene SCHEMBL8679594 | 0.90 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3274720 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL5835513 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869391-B1 | Heat-developable photographic materials | FUJI PHOTO FILM CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6027872-A | SUPPORT COATED WITH PHOTOSENSITIVE SILVER HALIDE, ORGANIC SILVER SALT, REDUCING AGENT AND A DISULFIDE COMPOUND FOR IMPROVED INFRARED SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 2000-02-22 | — | — | US | disclosed |
| US-6025122-A | MATERIAL COMPRISING REDUCIBLE SILVER SALT, REDUCING AGENT, CONTRAST ENHANCER, BINDER, THIOSULFONIC ACID OR ESTER COMPOUND; ULTRAHIGH CONTRAST, LOW FOG, MINIMIZED VARIATION OF PHOTOGRAPHIC CHARACTERISTICS WITH HEAT DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0869391-A1 | Heat-developable photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1998-10-07 | — | — | EP | disclosed |