SCHEMBL7555730

SCHEMBL7555730

CN1CCN=C1c1cccc(Oc2nc(Oc3cc(C(=N)N)ccc3O)c(F)c(NCC3CCN(CC(=O)O)CC3)c2F)c1

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.78
F2 P00734 14/20 0.78
F3 P13726 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576155 0.92 F10 (0.81) F10F2F3
SCHEMBL6579619 0.88 F10 (1.00) F10F2
SCHEMBL6579682 0.87 F10 (0.80) F10F2
SCHEMBL6578632 0.86 F10 (0.78) F10F2
SCHEMBL6581689 0.85 F10 (0.93) F10F2
SCHEMBL8068927 0.84 F10 (0.70) F10F2
SCHEMBL6578604 0.84 F10 (0.82) F10F2
SCHEMBL6578949 0.83 F10 (0.67) F10F2F3
Fidexaban SCHEMBL4354301 0.82 F10 (1.00) F10F2
Fidexaban SCHEMBL29381445 0.82 F10 (1.00) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853101-B1 Alkoxy-functional sealants with rapid development of green strength DOW CORNING (US) 2002-07-03 EP disclosed
EP-1141132-A1 RTV SILICONE COMPOSITIONS WITH RAPID DEVELOPMENT OF GREEN STRENGTH DOW CORNING CORPORATION (US) 2001-10-10 EP disclosed
US-6235832-B1 RTV silicone compositions with rapid development of green strength DOW CORNING CORPORATION 2001-05-22 US disclosed
US-6107435-A BLEND COMPRISING END GROUP-DERIVATIZED POLYSILOXANE, TITANIUM COMPOUND, AMINOFUNCTIONAL ALKOXYSILANE, AN ALKOXYSILANE DERIVATIVE, AND SILICA DOW CORNING CORPORATION (US) 2000-08-22 US disclosed
WO-2000037565-A1 RTV SILICONE COMPOSITIONS WITH RAPID DEVELOPMENT OF GREEN STRENGTH DOW CORNING CORPORATION (US) 2000-06-29 WO disclosed
EP-1008613-A2 Process for preparing room temperature vulcanizing silicone compositions DOW CORNING CORPORATION (US) 2000-06-14 EP disclosed
EP-0967246-A1 Silica filled RTV compositions having adhesion to glass and ceramic materials DOW CORNING CORPORATION (US) 1999-12-29 EP disclosed
US-5840794-A COMPOSITION COMPRISING MIXTURE OF POLYDIORGANOSILOXANE HAVING ALKOXYSILANE END GROUPS, TITANIUM CATALYST, FILLER, ALKOXYSILANE DOW CORNING CORPORATION (US) 1998-11-24 US disclosed
EP-0853101-A1 Alkoxy-functional sealants with rapid development of green strength DOW CORNING CORPORATION (US) 1998-07-15 EP disclosed