Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220314 | 0.76 | TAAR1 (0.39) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| SCHEMBL3914867 | 0.76 | TDP1 (0.36) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| SCHEMBL4242152 | 0.76 | TDP1 (0.36) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| Bromide SCHEMBL25226061 | 0.74 | TDP1 (0.35) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| SCHEMBL13176360 | 0.74 | TAAR1 (0.42) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| SCHEMBL8755559 | 0.74 | DPP4 (0.39) | TAAR1CYP2D6LMNADPP4F2 | |
| SCHEMBL14603796 | 0.74 | TDP1 (0.35) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| Hydrochloric Acid SCHEMBL2153907 | 0.74 | TDP1 (0.35) | TAAR1KDM4EADRA2AADRA2CCYP2D6 | |
| SCHEMBL14091955 | 0.74 | DPP4 (0.39) | TAAR1CYP2D6LMNADPP4F2 | |
| SCHEMBL4896021 | 0.72 | TAAR1 (0.41) | TAAR1KDM4EADRA2AADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288130-B2 | Polypeptide cleavage process | MEDTRONIC, INC. (US) | 2012-10-16 | — | — | US | claimed |
| EP-1532142-B1 | POLYPEPTIDE CLEAVAGE PROCESS | MEDTRONIC INC (US) | 2012-03-21 | — | — | EP | claimed |
| US-20100311947-A1 | POLYPEPTIDE CLEAVAGE PROCESS | MEDTRONIC, INC. (US) | 2010-12-09 | — | — | US | claimed |
| EP-1531836-B1 | POLYPEPTIDE CLEAVAGE PROCESS | MEDTRONIC INC (US) | 2010-11-10 | — | — | EP | claimed |
| US-7771966-B2 | Polypeptide cleavage process | MEDTRONIC, INC. (US) | 2010-08-10 | — | — | US | claimed |
| US-7592432-B2 | selectively splitting the polypeptide at a Cys-His site, by hydrolysis in presence of a palladium promotor dissolved in formic acid; purification with by-product inhibition | RESTORAGEN, INC. (US) | 2009-09-22 | — | — | US | claimed |
| EP-1531836-A4 | POLYPEPTIDE CLEAVAGE PROCESS | RESTORAGEN INC (US) | 2008-11-05 | — | — | EP | claimed |
| EP-1532142-A4 | POLYPEPTIDE CLEAVAGE PROCESS | RESTORAGEN INC (US) | 2007-08-08 | — | — | EP | claimed |
| US-20050227313-A1 | Polypeptide cleavage process | MEDTRONIC, INC. | 2005-10-13 | — | — | US | claimed |
| US-20050227314-A1 | Polypeptide cleavage process | MEDTRONIC, INC. | 2005-10-13 | — | — | US | claimed |
| EP-1532142-A2 | POLYPEPTIDE CLEAVAGE PROCESS | Restoragen, Inc. (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1531836-A2 | POLYPEPTIDE CLEAVAGE PROCESS | Restoragen, Inc. (US) | 2005-05-25 | — | — | EP | claimed |
| WO-2004011599-A2 | POLYPEPTIDE CLEAVAGE PROCESS | RESTORAGEN, INC. (US) | 2004-02-05 | — | — | WO | claimed |
| WO-2003100015-A2 | POLYPEPTIDE CLEAVAGE PROCESS | RESTORAGEN, INC. (US) | 2003-12-04 | — | — | WO | claimed |
| WO-2021106982-A1 | METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND | 丸善石油化学株式会社 | 2021-06-03 | — | — | WO | disclosed |