Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383784 | 0.88 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4519040 | 0.88 | KCNH2 (0.40) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4717888 | 0.87 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4510341 | 0.83 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1383988 | 0.81 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4506650 | 0.81 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6501943 | 0.81 | KCNH2 (0.40) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1382800 | 0.81 | KCNH2 (0.40) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6372004 | 0.80 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1383186 | 0.80 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |