Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558174 | 0.89 | DHODH (0.36) | DHODHCYP11B2CYP11B1 | |
| SCHEMBL7551780 | 0.87 | DHODH (0.40) | DHODHCRACR2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7553442 | 0.87 | DHODH (0.35) | DHODHCRACR2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7558187 | 0.82 | DHODH (0.35) | DHODHCRACR2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7550407 | 0.81 | DHODH (0.38) | DHODHCRACR2APDE10AEPHX2CHRNA7 | |
| SCHEMBL7559589 | 0.80 | NPC1 (0.36) | DHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7555059 | 0.79 | HPGD (0.35) | DHODHTAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL7556208 | 0.79 | STAT3 (0.38) | DHODH | |
| SCHEMBL8491101 | 0.77 | DHODH (0.37) | DHODHCRACR2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7555044 | 0.77 | DHODH (0.35) | DHODHCRACR2ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734380-B1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6369270-B1 | CHEMICAL INTERMEDIATES | RHONE POULENC AGRICULTURE LIMITED (GB) | 2002-04-09 | — | — | US | disclosed |
| US-6114538-A | 2-POSITION OF BENZOY RING OF 4-BENZOYLISOXAZOLE DERIVATIVE IS SUBSTITUTED AND PARTICULARLY USED AGAINST MONOCOTYLEDONOUS WEEDS BY POST-EMEREGENECE APPLICATION | RHONE POULENC AGRICULTURE LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| US-5998653-A | CHEMICAL INTERMEDIATE FOR HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1999-12-07 | — | — | US | disclosed |
| US-5658858-A | POSTEMERGENCE HERBICIDES | RHONE-POULENC ARGRICULTURE LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| CN-1137271-A | 4-benzoylisoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |