⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688485 | 0.75 | — | — | |
| SCHEMBL1993180 | 0.74 | — | — | |
| SCHEMBL4968761 | 0.69 | — | — | |
| SCHEMBL27267 | 0.65 | — | — | |
| SCHEMBL6006527 | 0.64 | MAPT (0.35) | — | |
| SCHEMBL2001816 | 0.63 | — | — | |
| SCHEMBL1792330 | 0.61 | — | — | |
| SCHEMBL81587 | 0.61 | — | — | |
| SCHEMBL8397970 | 0.61 | PAOX (0.31) | — | |
| SCHEMBL23758051 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882701-B1 | SUBSTITUTED AMIDE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6048894-A | FARNESYL-PROTEIN TRANSFERASE INHIBITORS, ANTITUMOR OR ANTICANCER AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0882701-A1 | SUBSTITUTED AMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |