Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478817 | 0.94 | PPARG (0.56) | PPARGAOC3HPGDALDH1A1MAPT | |
| SCHEMBL6183482 | 0.87 | HSD17B2 (0.60) | AOC3PTGESHDAC1HDAC6HSD17B1 | |
| SCHEMBL6185834 | 0.83 | AOC3 (0.58) | PPARGAOC3HPGDALDH1A1MAPT | |
| SCHEMBL6184250 | 0.81 | HSD17B2 (0.57) | AOC3HSD17B1HSD17B2KMT2A | |
| SCHEMBL6184961 | 0.79 | HSD17B2 (0.54) | AOC3PTGESHDAC1HDAC6HSD17B1 | |
| SCHEMBL6184749 | 0.79 | HSD17B2 (0.56) | PPARGAOC3ALDH1A1PTGESHDAC1 | |
| SCHEMBL6478851 | 0.79 | HSD17B2 (0.54) | AOC3HSD17B1HSD17B2KMT2A | |
| SCHEMBL3439044 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B1HSD17B2KMT2A | |
| SCHEMBL2847856 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B1HSD17B2KMT2A | |
| SCHEMBL6184066 | 0.78 | HSD17B2 (0.58) | AOC3HPGDPTGESHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |