Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557989 | 0.95 | FOLH1 (0.56) | FOLH1ANPEPENPEPDHODHGRM2 | |
| SCHEMBL999055 | 0.89 | FOLH1 (0.61) | FOLH1ANPEPENPEPDHODHMRGPRX4 | |
| SCHEMBL16559877 | 0.89 | FOLH1 (0.66) | FOLH1ANPEPENPEPMRGPRX4CYP2D6 | |
| Hydrochloric Acid SCHEMBL2636111 | 0.87 | FOLH1 (0.59) | FOLH1ANPEPENPEPDHODHGRM2 | |
| SCHEMBL7300545 | 0.86 | PARP1 (0.48) | FOLH1HTR6 | |
| SCHEMBL1980273 | 0.85 | FOLH1 (0.61) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL371526 | 0.85 | FOLH1 (0.70) | FOLH1ANPEPENPEPMRGPRX4CYP2D6 | |
| SCHEMBL5473039 | 0.84 | CYP4F2 (0.62) | FOLH1ANPEPENPEPDHODHCYP2D6 | |
| SCHEMBL9175315 | 0.83 | FOLH1 (0.54) | FOLH1ANPEPENPEPMRGPRX4CYP2D6 | |
| SCHEMBL18551279 | 0.82 | HDAC3 (0.63) | FOLH1ANPEPENPEPCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| WO-2002070680-A1 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| EP-1226237-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | claimed |
| WO-2001016300-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-08 | — | — | WO | claimed |
| EP-0254009-B1 | A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1991-04-17 | — | — | EP | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | disclosed |
| WO-2002070680-A1 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| EP-1226237-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001027077-A2 | HYDROXYSULFONYLALKYLENE-, PHOSPHONOALKYLENE- OR DIFLUORO(PHOSPHONONON)METHYL- SUBSTITUTED BENZENE, OR BENZOFURAN DERIVATIVES AS NON-PEPTIDIC CDC25 INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2001016300-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-08 | — | — | WO | disclosed |
| EP-0254009-B1 | A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1991-04-17 | — | — | EP | disclosed |
| US-4970343-A | CONTACTING IN LIQUID STATE WITH HYDROBROMIDE SALT OF AMINO-BENZOIC ACID ESTER, DEHYDRATING | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1990-11-13 | — | — | US | disclosed |
| EP-0194352-A2 | Salicylate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-09-17 | — | — | EP | disclosed |
| US-4537992-A | ACYLHALIDES AND AMINOBENZOATE ESTERS | AGAN CHEMICAL MANUFACTURERS, LTD. (IL) | 1985-08-27 | — | — | US | disclosed |