Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457141 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12069562 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417196 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7461634 | 0.78 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12068019 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7459799 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12069558 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12068798 | 0.75 | PDE10A (0.84) | PDE10A | |
| SCHEMBL12067698 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7451194 | 0.74 | PDE10A (0.76) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580207-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011154327-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | WO | disclosed |