Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.90 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5236916 | 0.99 | DPP4 (0.88) | DPP4KCNA5KCNH2MEN1CRHBP | |
| SCHEMBL5232770 | 0.95 | DPP4 (1.00) | DPP4KCNA5KCNH2 | |
| SCHEMBL5236714 | 0.88 | DPP4 (0.70) | DPP4KCNA5KCNH2MEN1CRHBP | |
| SCHEMBL5237400 | 0.87 | DPP4 (0.69) | DPP4KCNA5KCNH2MEN1CRHBP | |
| SCHEMBL5236399 | 0.86 | DPP4 (0.76) | DPP4KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL5241438 | 0.85 | DPP4 (0.74) | DPP4KCNA5KCNH2 | |
| SCHEMBL8947899 | 0.85 | DPP4 (1.00) | DPP4KCNA5KCNH2EGFRCA1 | |
| SCHEMBL5235622 | 0.84 | DPP4 (0.72) | DPP4KCNA5KCNH2 | |
| SCHEMBL5236388 | 0.82 | DPP4 (0.70) | DPP4KCNA5KCNH2 | |
| SCHEMBL6110970 | 0.82 | DPP4 (0.77) | DPP4KCNA5KCNH2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |