Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.51 |
| ▸ | RARA | P10276 | 5/20 | 0.48 |
| ▸ | RARG | P13631 | 7/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472245 | 1.00 | IKBKB (0.51) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL7564352 | 0.89 | IKBKB (0.48) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6477261 | 0.89 | IKBKB (0.48) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6473721 | 0.86 | IKBKB (0.48) | IKBKBRARARARGS1PR1 | |
| SCHEMBL7559814 | 0.86 | IKBKB (0.48) | IKBKBRARARARGS1PR1 | |
| SCHEMBL6477180 | 0.82 | IKBKB (0.45) | IKBKBRARARARGRARB | |
| SCHEMBL7562839 | 0.82 | IKBKB (0.45) | IKBKBRARARARGRARB | |
| SCHEMBL6033016 | 0.78 | IKBKB (0.60) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6033356 | 0.77 | IKBKB (0.62) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6033249 | 0.76 | IKBKB (0.51) | IKBKBRARARARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |