Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MPC2 | O95563 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183723 | 0.84 | FFAR1 (0.55) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6473659 | 0.83 | FFAR1 (0.52) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL5399580 | 0.79 | FFAR1 (0.61) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6185012 | 0.78 | FFAR1 (0.57) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL6183905 | 0.78 | FFAR1 (0.59) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL5399098 | 0.78 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6184172 | 0.78 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5392596 | 0.77 | FFAR1 (0.49) | FFAR1PPARGPPARAMAPTAOC3 | |
| SCHEMBL6182568 | 0.76 | FFAR1 (0.54) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6183077 | 0.76 | FFAR1 (0.52) | FFAR1PPARAMAPTAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |