Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 10/20 | 0.90 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.90 |
| ▸ | MYC | P01106 | 1/20 | 0.69 |
| ▸ | NAT1 | P18440 | 1/20 | 0.69 |
| ▸ | MAX | P61244 | 1/20 | 0.69 |
| ▸ | IGF1R | P08069 | 2/20 | 0.64 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559789 | 1.00 | PIM1 (0.90) | PIM1PIM2MYCNAT1MAX | |
| SCHEMBL261188 | 0.95 | PIM1 (1.00) | PIM1PIM2MYCNAT1MAX | |
| SCHEMBL261187 | 0.95 | PIM1 (1.00) | PIM1PIM2MYCNAT1MAX | |
| SCHEMBL2544039 | 0.95 | PIM1 (1.00) | PIM1PIM2MYCNAT1MAX | |
| SCHEMBL1248780 | 0.84 | PIM1 (0.83) | PIM1PIM2NAT1PIM3HPGD | |
| SCHEMBL1248782 | 0.84 | PIM1 (0.83) | PIM1PIM2NAT1PIM3HPGD | |
| SCHEMBL12891790 | 0.84 | PIM1 (0.83) | PIM1PIM2NAT1PIM3HPGD | |
| SCHEMBL1250231 | 0.82 | PIM1 (0.77) | PIM1PIM2NAT1IGF1RPIM3 | |
| SCHEMBL1250232 | 0.82 | PIM1 (0.77) | PIM1PIM2NAT1IGF1RPIM3 | |
| SCHEMBL20816059 | 0.81 | NAT1 (1.00) | PIM1PIM2MYCNAT1MAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | claimed |
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | disclosed |