SCHEMBL755988

SCHEMBL755988

Cc1cc(=O)oc2cc(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 1.00
CA9 Q16790 8/20 1.00
CA1 P00915 5/20 1.00
CA2 P00918 2/20 1.00
ALDH1A1 P00352 3/20 0.70
HSD17B10 Q99714 2/20 0.70
HPGD P15428 2/20 0.70
KDM4E B2RXH2 2/20 0.70
GLA P06280 1/20 0.70
MAPK1 P28482 1/20 0.70
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
IL2 P60568 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.56
ALDH1A2 O94788 1/20 0.56
ALDH2 P05091 1/20 0.56
ALDH1B1 P30837 1/20 0.56
MAPT P10636 1/20 0.55
CYP2C9 P11712 1/20 0.55
KMT2A Q03164 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260974 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL10048269 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL145332 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL15484273 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL1526661 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL15745917 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL2319034 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL165912 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL152641 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1
SCHEMBL1356276 1.00 CA12 (1.00) CA12CA9CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1573042-A1 METHOD FOR DETERMINING THE ENZYMATIC STATUS OF HUMAN SKIN IN VITRO Henkel Kommanditgesellschaft auf Aktien (DE) 2005-09-14 EP claimed
WO-2004058991-A1 METHOD FOR DETERMINING THE ENZYMATIC STATUS OF HUMAN SKIN IN VITRO HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO claimed
EP-0954560-A1 METHOD AND MEDIUM FOR DETECTING VANCOMYCIN-RESISTANT ENTEROCOCCUS IDEXX LABORATORIES, INC. (US) 1999-11-10 EP claimed
WO-1998004674-A1 METHOD AND MEDIUM FOR DETECTING VANCOMYCIN-RESISTANT $i(ENTEROCOCCUS) IDEXX LABORATORIES, INC. (US) 1998-02-05 WO claimed
EP-4408533-A1 OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES Zevra Denmark A/S (DK) 2024-08-07 EP disclosed
US-20240076660-A1 GENE CORRECTION OF POMPE DISEASE AND OTHER AUTOSOMAL RECESSIVE DISORDERS VIA RNA-GUIDED NUCLEASES WISCONSIN ALUMNI RESEARCH FOUNDATION 2024-03-07 US disclosed
US-11739320-B2 Gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-08-29 US disclosed
WO-2023073531-A1 GLYCOCONJUGATED DRUG FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) (AR) 2023-05-04 WO disclosed
WO-2023053008-A1 OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES KEMPHARM DENMARK A/S (DK) 2023-04-06 WO disclosed
WO-2022271944-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF GAUCHER DISEASE AVROBIO, INC. (US) 2022-12-29 WO disclosed
US-20220281908-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-09-08 US disclosed
WO-2021059058-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-04-01 WO disclosed
EP-0685458-A1 Glycolipid analogues as glucosidase inhibitors SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1995-12-06 EP disclosed
US-5089395-A High speed qualitative, quantitative analysis UNIVERSITY OF CINCINNATI (US) 1992-02-18 US disclosed
EP-0173255-B1 OLIGOSACCHARIDE DERIVATIVES AND THEIR USE AS SUBSTRATE FOR MEASURING ALPHA-AMYLASE ACTIVITY WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-17 EP disclosed
US-4762917-A AMINO SUBSTITUTED WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1988-08-09 US disclosed
EP-0215066-A1 VIABLE MICROORGANISM DETECTION BY INDUCED FLUORESCENCE UNIVERSITY OF CINCINNATI (US) 1987-03-25 EP disclosed
WO-1986005206-A1 VIABLE MICROORGANISM DETECTION BY INDUCED FLUORESCENCE UNIVERSITY OF CINCINNATI (US) 1986-09-12 WO disclosed
EP-0173255-A2 Oligosaccharide derivatives and their use as substrate for measuring alpha-amylase activity WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-05 EP disclosed
US-4231750-A Methods for performing chemical assays using fluorescence and photon counting DIAGNOSTIC REAGENTS, INC. (US) 1980-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281908-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS ALPG, UNG, UGDH CA12 1975/4885CA9 1573/4885CA1 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.