Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808714 | 0.80 | KDM4E (0.51) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL28731822 | 0.80 | KDM4E (0.49) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL2549892 | 0.79 | KDM4E (0.50) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL312298 | 0.78 | SRD5A2 (0.53) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL29622719 | 0.76 | TSHR (0.65) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL51027 | 0.76 | TSHR (0.65) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL1450228 | 0.75 | PARP10 (0.39) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL7105778 | 0.75 | PRKCI (0.56) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL12296530 | 0.75 | CA12 (0.48) | KDM4ELMNASMN1; SMN2CA12CA1 | |
| SCHEMBL22775248 | 0.75 | CA12 (0.48) | KDM4ELMNASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882011-B1 | PROCESS FOR PREPARING N-(3-AMINO-4-CHLOROPHENYL) ACYLAMIDES | EASTMAN CHEM CO (US) | 2002-03-27 | — | — | EP | claimed |