Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466144 | 1.00 | CCR8 (0.53) | CCR8KCNH2GRIN1GRIN2BGAA | |
| Oxalic Acid SCHEMBL7728019 | 0.97 | CCR8 (0.52) | CCR8KCNH2GRIN1GRIN2B | |
| SCHEMBL7455480 | 0.92 | CCR8 (0.53) | CCR8KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL7725846 | 0.91 | CCR8 (0.53) | CCR8KCNH2 | |
| SCHEMBL7724893 | 0.91 | CCR8 (0.52) | CCR8KCNH2 | |
| SCHEMBL7724897 | 0.91 | CCR8 (0.52) | CCR8KCNH2 | |
| SCHEMBL7728026 | 0.90 | CCR8 (0.52) | CCR8KCNH2 | |
| SCHEMBL7731901 | 0.90 | CCR8 (0.51) | CCR8KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL7462927 | 0.89 | CCR8 (0.54) | CCR8KCNH2 | |
| SCHEMBL7724509 | 0.89 | CCR8 (0.51) | CCR8KCNH2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |