Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529513 | 0.83 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL3288477 | 0.82 | MEN1 (0.65) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL8172216 | 0.81 | MEN1 (0.64) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL28467635 | 0.80 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL641425 | 0.79 | MEN1 (0.59) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL18030731 | 0.77 | MAPT (0.52) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL31135773 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL3222110 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL31654213 | 0.75 | MAPT (0.52) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL6192945 | 0.75 | MAPT (0.61) | SMN1; SMN2MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |