Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.71 |
| ▸ | AR | P10275 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.55 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20870226 | 0.87 | MAP2K1 (0.69) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL24876966 | 0.84 | MAP2K1 (0.70) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL29456888 | 0.84 | AR (0.76) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL145055 | 0.84 | AR (0.76) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL3043823 | 0.83 | MAP2K1 (1.00) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL31331937 | 0.81 | AR (0.64) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL15031015 | 0.81 | CYP1A2 (0.53) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL31331892 | 0.80 | AR (0.62) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL27509862 | 0.80 | MAP2K1 (0.64) | MAP2K1ARALDH1A1HSD17B3KDM4E | |
| SCHEMBL14176755 | 0.80 | MAP2K1 (0.75) | MAP2K1ARALDH1A1HSD17B3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019068538-A1 | NOVEL COMPOUNDS AND THEIR USE AS SELECTIVE INHIBITORS OF CASPASE-2 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-04-11 | — | — | WO | disclosed |
| US-9221759-B2 | Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221759-B2 | Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-12-29 | — | — | US | disclosed |
| US-9012166-B2 | Method for assaying histone methylation enzyme activity | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20130202536-A1 | FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130202536-A1 | FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130029878-A1 | Method for Assaying Histone Methylation Enzyme Activity | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2013-01-31 | — | — | US | disclosed |
| EP-1196822-A1 | MARKED, DIFFICULT-TO-COUNTERFEIT DOCUMENTS | Inksure Ltd. (IL) | 2002-04-17 | — | — | EP | disclosed |
| WO-2000079347-A1 | MARKED, DIFFICULT-TO-COUNTERFEIT DOCUMENTS | INKSURE LTD. (IL) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029878-A1 | Method for Assaying Histone Methylation Enzyme Activity | EHMT1, DOT1L, EHMT2 | MAP2K1 1269/4885AR 2427/4885ALDH1A1 1742/4885 |
| US-20130202536-A1 | FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY | CLTA, LARS1, SSB | MAP2K1 4800/4885AR 4549/4885ALDH1A1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.