Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MPC2 | O95563 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181997 | 0.94 | FFAR1 (0.49) | FFAR1HSD17B2HSD17B1PPARGMPC2 | |
| SCHEMBL6181638 | 0.92 | FFAR1 (0.52) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL6184172 | 0.85 | FFAR1 (0.59) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL5399098 | 0.85 | FFAR1 (0.59) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL5403696 | 0.84 | FFAR1 (0.56) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL6183498 | 0.84 | HSD17B2 (0.53) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL5760451 | 0.84 | FFAR1 (0.55) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL6182440 | 0.84 | HSD17B2 (0.57) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL5399315 | 0.84 | HSD17B2 (0.57) | FFAR1HSD17B2HSD17B1AOC3PPARG | |
| SCHEMBL6185090 | 0.83 | FFAR1 (0.52) | FFAR1HSD17B2HSD17B1AOC3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |