Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766514 | 1.00 | GRM6 (0.41) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5768050 | 1.00 | GRM6 (0.41) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5766511 | 1.00 | GRM6 (0.41) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5770902 | 1.00 | GRM6 (0.41) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL6999013 | 0.87 | ADORA1 (0.43) | ADORA1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5838542 | 0.87 | ADORA1 (0.43) | ADORA1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5768503 | 0.87 | GRM6 (0.37) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5768500 | 0.87 | GRM6 (0.37) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5769847 | 0.87 | GRM6 (0.37) | GRM6ADORA1MAPTMEN1LMNA | |
| SCHEMBL5837158 | 0.85 | ADORA1 (0.38) | GRM6ADORA1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151561-A1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151561-A1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | PTPRO, PTPN1, PTPRS | GRM6 2745/4885ADORA1 1290/4885MAPT 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.