SCHEMBL7560943

SCHEMBL7560943

CCCCCCc1cnc(-c2ccc(OCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)nc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.46
RAB9A P51151 7/20 0.43
MAPT P10636 5/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 5/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
STAT3 P40763 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6975888 1.00 RARB (0.46) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7560022 0.99 RARB (0.45) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7558804 0.99 RARB (0.45) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7082095 0.93 RARB (0.48) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7755270 0.92 RARB (0.46) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7755473 0.92 RARB (0.46) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7157202 0.91 RARB (0.42) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL8428768 0.91 RARB (0.42) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7557738 0.91 RARB (0.42) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7089855 0.91 RARB (0.42) RARBRAB9AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
EP-0646636-B1 Liquid crystal compounds having a fluoroether terminal portion MINNESOTA MINING & MFG (US) 2000-08-23 EP disclosed
US-5933128-A Chiral smectic liquid crystal apparatus and driving method therefor CANON KABUSHIKI KAISHA (JP) 1999-08-03 US disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-5437812-A Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-01 US disclosed
EP-0646636-A1 Liquid crystal compounds having a fluoroether terminal portion MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-05 EP disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed
US-5262082-A Ferroelectric liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
WO-1993022396-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-11 WO disclosed