SCHEMBL7560946

SCHEMBL7560946

CCCCCCc1cnc(-c2ccc(OC(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.43
RAB9A P51151 7/20 0.41
MAPT P10636 5/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
NPC1 O15118 5/20 0.35
STAT3 P40763 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7560700 1.00 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7560026 0.99 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7755477 0.92 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7755275 0.92 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7750806 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7756924 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7756880 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7754433 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7750801 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL7756939 0.91 RARB (0.43) RARBRAB9AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
US-5933128-A Chiral smectic liquid crystal apparatus and driving method therefor CANON KABUSHIKI KAISHA (JP) 1999-08-03 US disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
EP-0579545-B1 Liquid crystal display device MINNESOTA MINING & MFG (US) 1997-03-12 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-5437812-A Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-01 US disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed
US-5377033-A Ferroelectric liquid crystal device with an organosilesquioxane alignment layer and a polyamide or polyester alignment layer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-12-27 US disclosed
EP-0579545-A1 Liquid crystal display device MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-19 EP disclosed
US-5262082-A Ferroelectric liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
WO-1993022396-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-11 WO disclosed