SCHEMBL7560964

SCHEMBL7560964

CCOC(=O)c1c(Cl)cccc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA7 P43166 2/20 0.54
CA9 Q16790 2/20 0.54
CA14 Q9ULX7 2/20 0.54
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
KDM4E B2RXH2 2/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
GRM6 O15303 1/20 0.49
ALDH1A1 P00352 2/20 0.47
PDE4B Q07343 1/20 0.47
RXFP1 Q9HBX9 1/20 0.46
ALOX5 P09917 1/20 0.46
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455857 0.88 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL8493097 0.86 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL17502608 0.85 TSHR (0.50) CA12CA1CA2CA7CA9
SCHEMBL282595 0.83 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL10157282 0.83 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL20830632 0.82 KMT2A (0.52) CA12CA1CA2CA7CA9
SCHEMBL10562280 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL16041589 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL4943629 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL30822598 0.81 CA12 (0.54) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1300084-C 2-methoxy diphenyl ketone compound intermediate and its preparation method AMERICAN CYANAMID CO (US) 2007-02-14 CN disclosed
CN-1495153-A 2-methoxy diphenyl ketone compound intermediate and its preparation method 2004-05-12 CN disclosed
CN-1147456-C Fungicidal 2-methoxybenzophenones 2004-04-28 CN disclosed
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
CN-1217317-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID CO (US) 1999-05-26 CN disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed