Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175278 | 0.94 | CYP19A1 (0.53) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27596786 | 0.79 | HPGD (0.61) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6141996 | 0.78 | HTT (0.59) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL29910107 | 0.78 | HTT (0.59) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL840298 | 0.77 | SKP2 (0.42) | SKP2CYP19A1ALOX5 | |
| Phosphine SCHEMBL27961207 | 0.76 | HTT (0.57) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL3319483 | 0.76 | HTT (0.67) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL11818683 | 0.76 | HTT (0.47) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27791051 | 0.74 | HTT (0.55) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9283660 | 0.74 | TYR (0.47) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864557-B1 | Industrial process for the continuous production of sodium orthohydroxymandelate | CLARIANT FRANCE SA (FR) | 2002-01-30 | — | — | EP | disclosed |
| EP-0864557-A1 | Industrial process for the continuous production of sodium orthohydroxymandelate | Clariant (France) S.A. (FR) | 1998-09-16 | — | — | EP | disclosed |