SCHEMBL7560992

SCHEMBL7560992

CC(=O)N1CCN(c2ccc(N3CC(CNC(C)=S)OC3=O)cc2F)CC1

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.74
MAOA P21397 4/20 0.74
PTGS1 P23219 2/20 0.70
SDHA P31040 2/20 0.70
LMNA P02545 1/20 0.70
CALML3 P27482 1/20 0.70
F10 P00742 10/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7560985 1.00 MAOB (0.74) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7710392 0.94 MAOB (0.71) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7710394 0.94 MAOB (0.71) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7710086 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7710092 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6251170 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7707235 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6251173 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7707238 0.93 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL7712606 0.92 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020016323-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality PHARMACIA & UPJOHN COMPANY 2002-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016323-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality OXA1L, MRPL21, TOP1 MAOB 2998/4885MAOA 3306/4885PTGS1 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.