Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341246 | 0.91 | KMT2A (0.62) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL3130690 | 0.82 | KMT2A (0.60) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL1962256 | 0.82 | KMT2A (0.60) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL862990 | 0.79 | KMT2A (0.60) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL30223355 | 0.75 | SMN1; SMN2 (0.64) | KMT2AHPGDSMN1; SMN2USP2KDM4E | |
| SCHEMBL4812101 | 0.75 | SMN1; SMN2 (0.64) | KMT2AHPGDSMN1; SMN2USP2KDM4E | |
| SCHEMBL30223215 | 0.75 | SMN1; SMN2 (0.64) | KMT2AHPGDSMN1; SMN2USP2KDM4E | |
| SCHEMBL10310295 | 0.75 | SMN1; SMN2 (0.54) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL13973608 | 0.75 | KMT2A (0.64) | KMT2AHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6905952 | 0.75 | KMT2A (0.55) | KMT2AHPGDSMN1; SMN2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839059-B1 | CARDIOTROPIC RADIOPHARMACEUTICALS COMPRISING A TRANSITION METAL NITRIDE COMPLEX AND HAVING RAPID MYOCARDIAL CLEARANCE | CIS BIO INT (FR) | 2002-04-17 | — | — | EP | claimed |