Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561169 | 1.00 | NPC1 (0.34) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7556614 | 0.99 | NPC1 (0.35) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7556617 | 0.99 | NPC1 (0.35) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7562655 | 0.95 | NPC1 (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7554846 | 0.95 | NPC1 (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7562650 | 0.95 | NPC1 (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7554850 | 0.95 | NPC1 (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7553881 | 0.92 | NPC1 (0.34) | NPC1RAB9AKDM4ETP53ALDH1A1 | |
| SCHEMBL7553876 | 0.92 | NPC1 (0.34) | NPC1RAB9AKDM4ETP53ALDH1A1 | |
| SCHEMBL7555050 | 0.91 | NPC1 (0.34) | NPC1RAB9AKDM4ETP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708165-B1 | Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL CO (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6246452-B1 | FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-12 | — | — | US | disclosed |
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0708165-A1 | Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |