Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117 | 0.87 | CYP1A2 (0.45) | CYP1A2SLC29A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7561776 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19CXCR2 | |
| SCHEMBL16146619 | 0.80 | SLC29A1 (0.40) | CYP1A2SLC29A1CYP2D6JAK2JAK1 | |
| SCHEMBL16145765 | 0.79 | SLC29A1 (0.42) | CYP1A2SLC29A1CYP2D6JAK2JAK1 | |
| SCHEMBL21788563 | 0.79 | SLC29A1 (0.39) | CYP1A2SLC29A1CYP2D6MEN1POLB | |
| SCHEMBL16146189 | 0.79 | CYP1A2 (0.42) | CYP1A2SLC29A1UTS2RALDH1A1KDM4E | |
| SCHEMBL17635063 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL150046 | 0.74 | CYP1A2 (0.55) | CYP1A2SLC29A1CYP3A4MEN1POLB | |
| SCHEMBL4408534 | 0.72 | HSP90AA1 (0.39) | ALDH1A1KDM4EHTTHPGD | |
| SCHEMBL28766923 | 0.72 | KDM4E (0.34) | CYP1A2SLC29A1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022824-A2 | ASHBYA GOSSYPII GENES CODING FOR PROTEINS INVOLVED IN MEMBRANE TRANSPORT | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |