Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801196 | 1.00 | ADRB3 (0.62) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL7119535 | 0.91 | ADRB3 (0.69) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6797866 | 0.91 | ADRB3 (0.69) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| Methane SCHEMBL7561825 | 0.86 | ADRB3 (0.44) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7117954 | 0.82 | ADRB3 (0.66) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL7538705 | 0.82 | ADRB3 (0.66) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6802958 | 0.81 | ADRB3 (0.67) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6802964 | 0.81 | ADRB3 (0.67) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6800160 | 0.80 | ADRB3 (0.65) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6800153 | 0.80 | ADRB3 (0.65) | ADRB3ADRB1ADRB2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006274-A1 | N-(4-SULFONYLARYL)CYCLYLAMINE-2-HYDROXYETHYLAMINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |