Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562233 | 1.00 | KDM4E (0.30) | KDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL3620305 | 0.88 | KDM4E (0.30) | KDM4ETDP1 | |
| SCHEMBL5515979 | 0.88 | KDM4E (0.30) | KDM4ETDP1 | |
| SCHEMBL3620304 | 0.88 | KDM4E (0.30) | KDM4ETDP1 | |
| SCHEMBL7567236 | 0.84 | — | — | |
| SCHEMBL6419510 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5418078 | 0.83 | — | — | |
| SCHEMBL5420015 | 0.81 | KDM4E (0.32) | KDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL7561004 | 0.74 | DPP4 (0.34) | — | |
| SCHEMBL7561003 | 0.74 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |