Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562629 | 0.89 | MAPT (0.35) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL2450269 | 0.87 | MAPT (0.45) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL2450267 | 0.87 | MAPT (0.45) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL7764698 | 0.87 | MAPT (0.45) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL9804837 | 0.86 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL9231233 | 0.86 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL9231227 | 0.86 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL8903722 | 0.85 | MAPT (0.39) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL8903717 | 0.85 | MAPT (0.39) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL8903727 | 0.85 | MAPT (0.39) | SMN1; SMN2NPC1RAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077981-B1 | NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | LG CHEMICAL LTD (KR) | 2002-08-07 | — | — | EP | disclosed |