Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755980 | 0.89 | NR3C2 (0.56) | NR3C2ARBRD4PGR | |
| SCHEMBL754215 | 0.87 | NR3C2 (0.61) | NR3C2ARBRD4PGR | |
| SCHEMBL756053 | 0.86 | NR3C2 (0.51) | NR3C2ARBRD4 | |
| SCHEMBL754664 | 0.86 | NR3C2 (0.59) | NR3C2ARBRD4PGR | |
| SCHEMBL754681 | 0.85 | NR3C2 (0.53) | NR3C2ARPGR | |
| SCHEMBL755391 | 0.85 | NR3C2 (0.72) | NR3C2ARBRD4PGR | |
| SCHEMBL758564 | 0.84 | NR3C2 (0.69) | NR3C2BRD4PGR | |
| SCHEMBL756893 | 0.82 | NR3C2 (0.55) | NR3C2ARBRD4 | |
| SCHEMBL755896 | 0.82 | AR (0.58) | NR3C2AR | |
| SCHEMBL755535 | 0.82 | NR3C2 (0.54) | NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-B9 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | claimed |
| EP-1984345-B1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-08-31 | — | — | EP | claimed |