Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560460 | 1.00 | TSHR (0.65) | TSHRSIGMAR1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL862231 | 0.90 | TSHR (0.65) | TSHRSIGMAR1CYP11B1CYP11B2CYP19A1 | |
| Resorcinol SCHEMBL7559136 | 0.84 | TSHR (0.46) | TSHRHPGDBCL2L1BADDRD4 | |
| Resorcinol SCHEMBL7561949 | 0.84 | TSHR (0.46) | TSHRHPGDBCL2L1BADDRD4 | |
| SCHEMBL29358070 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 | |
| SCHEMBL8355 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 | |
| SCHEMBL27692545 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 | |
| SCHEMBL11606739 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 | |
| SCHEMBL385555 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 | |
| SCHEMBL11645158 | 0.81 | TSHR (1.00) | TSHRSIGMAR1HTR2CHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384113-B1 | POLYMER STABILIZER; LOW VOLATILITY; WEATHERABILITY; YELLOWING RESISTANCE | CYTEC TECHNOLOGY CORP. | 2002-05-07 | — | — | US | disclosed |
| US-20020028937-A1 | Benzocycle-substituted triazine and pyrimidine ultraviolet light absorbers | CYTEC TECHNOLOGY CORP. | 2002-03-07 | — | — | US | disclosed |
| US-6297377-B1 | Benzocycle-substituted triazine and pyrimidine ultraviolet light absorbers | CYTEC TECHNOLOGY CORPORATION | 2001-10-02 | — | — | US | disclosed |
| EP-1089987-A1 | BENZOCYCLE-SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067225-A1 | BENZOCYCLE-SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028937-A1 | Benzocycle-substituted triazine and pyrimidine ultraviolet light absorbers | ERCC5, ERCC4, ERCC2 | TSHR 1732/4885SIGMAR1 1960/4885CYP11B1 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.