Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5237614 | 0.99 | DPP4 (0.51) | DPP4APPKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5237626 | 0.99 | DPP4 (0.51) | DPP4APPKDM4EALDH1A1MEN1 | |
| SCHEMBL300189 | 0.88 | DPP4 (0.65) | DPP4 | |
| SCHEMBL300190 | 0.88 | DPP4 (0.65) | DPP4 | |
| Hydrochloric Acid SCHEMBL5235042 | 0.87 | DPP4 (0.66) | DPP4 | |
| Hydrochloric Acid SCHEMBL5235024 | 0.87 | DPP4 (0.66) | DPP4 | |
| SCHEMBL5236373 | 0.86 | DPP4 (0.40) | DPP4APPKDM4EALDH1A1MEN1 | |
| SCHEMBL5236382 | 0.86 | DPP4 (0.40) | DPP4APPKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5239949 | 0.85 | DPP4 (0.49) | DPP4APPKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5239959 | 0.85 | DPP4 (0.49) | DPP4APPKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |