SCHEMBL7564329

SCHEMBL7564329

CCCC=C(C(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.46
GRIK2 Q13002 2/20 0.46
EP300 Q09472 1/20 0.39
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 1/20 0.34
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564325 1.00 GRIK1 (0.46) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL7564268 0.86 EP300 (0.50) GRIK1EP300CYP1A2TSHRCHRM1
SCHEMBL7564265 0.86 EP300 (0.50) GRIK1EP300CYP1A2TSHRCHRM1
SCHEMBL16697925 0.85 GRIK1 (0.50) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL7559084 0.85 GRIK1 (0.42) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL19398819 0.85 GRIK1 (0.46) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL28427344 0.85 GRIK1 (0.46) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL7559080 0.85 GRIK1 (0.42) GRIK1GRIK2EP300ALDH1A1CYP1A2
SCHEMBL3269636 0.83 EP300 (0.62) EP300CYP1A2CHRM1TDP1CYP2C19
SCHEMBL14127265 0.83 EP300 (0.62) EP300CYP1A2CHRM1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
US-6030930-A USEFUL IN LUBRICATING OILS, AND TO CONCENTRATES CONTAINING THE OIL-SOLUBLE DISPERSANT ADDITIVES EXXON CHEMICAL PATENTS INC (US) 2000-02-29 US disclosed
US-6022929-A FUNCTIONALIZATION EXXON CHEMICAL PATENTS INC. (US) 2000-02-08 US disclosed
EP-0441548-B1 Process for producing ethylene alpha-olefin polymer substituted mono- and dicarboxylic acid dispersant additives INFINEUM USA LP (US) 1999-09-01 EP disclosed
CN-1042950-C Novel ethylene alpha-olefin polymer substituted amine dispersant additives EXXON CHEMICAL PATENTS INC (US) 1999-04-14 CN disclosed
EP-0900238-A1 ETHYLENE/ALPHA-OLEFIN/DIENE INTERPOLYMER-SUBSTITUTED CARBOXYLIC ACID DISPERSANT ADDITIVES EXXON CHEMICAL PATENTS, INC. (US) 1999-03-10 EP disclosed
EP-0892818-A1 AMIDOAMINE DERIVATIVES OF CARBOXYLIC AND THIOCARBOXYLIC-FUNCTIONALIZED HYDROCARBON POLYMERS EXXON CHEMICAL PATENTS, INC. (US) 1999-01-27 EP disclosed
US-5814715-A LUBRICATING OIL CONCENTRATES; OIL ADDITIVES; DISPERSANTS; POLYMERIZED RAFFINATE II STREAMS USING A LEWIS ACID CATALYST AND BROMINE-CONTAINING PROMOTER EXXON CHEMICAL PATENTS INC (US) 1998-09-29 US disclosed
US-5759967-A LUBRICATING OIL ADDITIVES EXXON CHEMICAL PATENTS INC (US) 1998-06-02 US disclosed
US-5747596-A GRAFT POLYMERIZATION OF CARBOXYLIC ACID PRODUCING MOIETIES ON OLEFIN POLYMER IN THE PRESENCE OF FREE RADICAL CATALYST AND POSTTREATMENT WITH AMINE EXXON CHEMICAL PATENTS INC. (US) 1998-05-05 US disclosed
US-4954572-A OIL ADDITIVES EXXON CHEMICAL PATENTS INC. (US) 1990-09-04 US disclosed
EP-0372709-A1 Improved dispersant additives prepared from monoepoxy alcohols EXXON CHEMICAL PATENTS INC. (US) 1990-06-13 EP disclosed
EP-0369641-A1 Improved dispersant additives prepared from monoepoxy thiols EXXON CHEMICAL PATENTS INC. (US) 1990-05-23 EP disclosed
EP-0368548-A1 Improved amide dispersant additives derived from amido-amines EXXON CHEMICAL PATENTS INC. (US) 1990-05-16 EP disclosed
EP-0357217-A2 Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-03-07 EP disclosed
EP-0356010-A1 Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-28 EP disclosed
EP-0353935-A1 Ethylene alpha-olefin polymer substituted mono-and dicarboxylic acid lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-07 EP disclosed
EP-0336664-A2 Improved dispersant additives derived from amido-amine adducts EXXON CHEMICAL PATENTS INC. (US) 1989-10-11 EP disclosed
US-4857217-A ADDUCT OF POLYOLEFIN MODIFIED WITH AN ACID AND POLYAMINE MODIFIED WITH (THIO)AMIDO COMPOUND EXXON CHEMICAL PATENTS INC. (US) 1989-08-15 US disclosed
EP-0319229-A2 Improved dispersant additives derived from amido-amines EXXON CHEMICAL PATENTS INC. (US) 1989-06-07 EP disclosed