Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254741 | 0.89 | TLR7 (0.51) | TLR7HASPINMAPTALDH1A1LMNA | |
| SCHEMBL16019753 | 0.84 | TLR7 (0.47) | TLR7HASPINMAPTALDH1A1LMNA | |
| SCHEMBL28508746 | 0.82 | HASPIN (0.39) | TLR7HASPINMAPTALDH1A1LMNA | |
| SCHEMBL28429276 | 0.82 | TLR7 (0.34) | TLR7 | |
| SCHEMBL1829942 | 0.80 | HASPIN (0.44) | TLR7HASPINMAPTALDH1A1LMNA | |
| SCHEMBL14889085 | 0.80 | TLR7 (0.45) | TLR7HASPINMAPTALDH1A1KMT2A | |
| SCHEMBL22130771 | 0.80 | TLR7 (0.45) | TLR7HASPINMAPTLMNAHTT | |
| SCHEMBL2459755 | 0.80 | KMT2A (0.41) | HASPINMAPTALDH1A1LMNAHPGD | |
| SCHEMBL16142515 | 0.79 | TLR7 (0.44) | TLR7HASPINMAPTALDH1A1KMT2A | |
| SCHEMBL20997798 | 0.79 | TLR7 (0.54) | TLR7HASPINMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978327-B | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109641904-B | 7-substituted sulfoxy-purinone compounds for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111978327-A | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-2755957-B2 | SYNTHESIS OF TRIAZOLOPYRIMIDINE COMPOUNDS | LEK PHARMACEUTICALS (SI) | 2019-05-15 | — | — | EP | disclosed |
| EP-1232172-A1 | NOVEL RIBOSE COMPOUNDS | AstraZeneca AB (SE) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036438-A1 | NOVEL RIBOSE COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-25 | — | — | WO | disclosed |