Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.72 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561896 | 1.00 | ADRB3 (0.72) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7114781 | 0.86 | ADRB3 (0.76) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7560539 | 0.84 | KMT2A (0.56) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7560531 | 0.84 | KMT2A (0.56) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7560522 | 0.84 | KMT2A (0.56) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL13719534 | 0.84 | ADRB3 (0.68) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7116296 | 0.83 | ADRB3 (0.79) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL11009261 | 0.81 | PLA2G4B (0.54) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7560252 | 0.79 | ADRB3 (1.00) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL7560260 | 0.79 | ADRB3 (1.00) | ADRB3ADRB1ADRB2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072760-A2 | PCRA HELICASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-19 | — | — | WO | claimed |