SCHEMBL7566352

SCHEMBL7566352

CNC(=O)/C(=N\OC)c1ccccc1COc1cccc(F)n1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.48
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
PDCD1 Q15116 2/20 0.33
CD274 Q9NZQ7 2/20 0.33
MAPT P10636 1/20 0.32
KCNH2 Q12809 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
PLA2G1B P04054 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7566354 1.00 HIF1A (0.48) HIF1ACYP11B1CYP11B2PDCD1CD274
SCHEMBL8370701 0.89 HIF1A (0.51) HIF1APDCD1CD274
SCHEMBL8370696 0.89 HIF1A (0.51) HIF1APDCD1CD274
SCHEMBL8780118 0.89 HIF1A (0.51) HIF1APDCD1CD274
SCHEMBL8372363 0.87 HIF1A (0.48) HIF1ACYP11B1CYP11B2PDCD1CD274
SCHEMBL8372364 0.87 HIF1A (0.48) HIF1ACYP11B1CYP11B2PDCD1CD274
SCHEMBL8780047 0.87 HIF1A (0.48) HIF1ACYP11B1CYP11B2PDCD1CD274
SCHEMBL7885086 0.87 HIF1A (0.46) HIF1APDCD1CD274
SCHEMBL8368320 0.87 HIF1A (0.48) HIF1AMRGPRX4
SCHEMBL8368318 0.87 HIF1A (0.48) HIF1AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring CANADA EMILY J (US) 2002-08-22 US disclosed
US-6432990-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 US disclosed
US-6369083-B1 2-methoxyimino-2 (pyrinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring DOW AGROSCIENCES LLC 2002-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring AADAC, MIDEAS, CNPY2 HIF1A 4745/4885CYP11B1 2970/4885CYP11B2 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.