Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076162 | 0.88 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11ULK1 | |
| SCHEMBL7076164 | 0.88 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11ULK1 | |
| SCHEMBL7079600 | 0.76 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11ULK1 | |
| SCHEMBL7082594 | 0.76 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11ULK1 | |
| SCHEMBL7079509 | 0.74 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7079512 | 0.74 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7081916 | 0.74 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7081913 | 0.74 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7571963 | 0.74 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7566944 | 0.74 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |