Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7566913

COc1ccc2ccc(S(=O)(=O)N(C)[C@H]3CCN(Cc4cc(C(=N)N)ccc4N)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.89
F2 P00734 12/20 0.89
KLK6 Q92876 1/20 0.64
PLG P00747 2/20 0.63
PLAT P00750 2/20 0.63
PROC P04070 2/20 0.63
PRSS1 P07477 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2328846 1.00 F10 (0.89) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2333281 0.91 F10 (0.91) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL7423997 0.87 F10 (0.74) F10F2KLK6
Trifluoroacetic Acid SCHEMBL2332758 0.87 KLK6 (0.70) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2332752 0.87 KLK6 (0.70) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2326764 0.85 KLK6 (0.89) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2326762 0.85 KLK6 (0.89) F10F2KLK6PLGPLAT
SCHEMBL8029502 0.84 F10 (0.78) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2328333 0.84 F10 (0.89) F10F2KLK6PLGPLAT
Trifluoroacetic Acid SCHEMBL2328852 0.84 F10 (0.72) F10F2KLK6PLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894088-A4 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2001-12-05 EP disclosed
US-6034093-A Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 2000-03-07 US disclosed
EP-0894088-A1 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-02-03 EP disclosed
WO-1998024784-A1 SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-11 WO disclosed