Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501194 | 0.95 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL21999362 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL7824612 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL21998688 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL7821193 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL7822881 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL12430335 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL21998902 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL11221078 | 0.91 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL10969527 | 0.87 | KDM4E (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611814-B | Compound containing 2-amino imidazole ring, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2024-11-19 | — | — | CN | claimed |
| CN-115611814-A | Compound containing 2-aminoimidazole ring and preparation method and application thereof | 烟台新药创制山东省实验室 | 2023-01-17 | — | — | CN | claimed |
| CN-115611814-B | Compound containing 2-amino imidazole ring, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2024-11-19 | — | — | CN | disclosed |
| CN-115611814-A | Compound containing 2-aminoimidazole ring and preparation method and application thereof | 烟台新药创制山东省实验室 | 2023-01-17 | — | — | CN | disclosed |
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |