Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079590 | 0.91 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7079596 | 0.91 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7079458 | 0.88 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7083133 | 0.85 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7083138 | 0.85 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7074446 | 0.83 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7074444 | 0.83 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7079594 | 0.79 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7082408 | 0.78 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11F10 | |
| SCHEMBL7083135 | 0.78 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |