Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844970 | 0.96 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1ALOX5APMAPT | |
| SCHEMBL4848377 | 0.94 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL4846550 | 0.93 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL4841446 | 0.85 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4849911 | 0.84 | CYSLTR1 (0.48) | CYSLTR1GPBAR1ALOX5APMAPTTDP1 | |
| SCHEMBL4848359 | 0.83 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4848197 | 0.83 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2ALOX5APMAPTTDP1 | |
| SCHEMBL14045446 | 0.82 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2GPBAR1ALOX5APMAPT | |
| SCHEMBL4850064 | 0.82 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4841568 | 0.82 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2ALOX5APMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177187-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064888-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |