Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SQLE | Q14534 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560951 | 0.92 | KMT2A (0.59) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL8100815 | 0.92 | KMT2A (0.59) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL7582329 | 0.92 | KMT2A (0.59) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL8106579 | 0.92 | KMT2A (0.59) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL10398391 | 0.77 | TSHR (0.50) | TSHRKMT2ASQLEMEN1CYP3A4 | |
| SCHEMBL3019606 | 0.74 | TSHR (0.47) | TSHRKMT2ASQLEMEN1CYP3A4 | |
| SCHEMBL4899765 | 0.73 | — | — | |
| SCHEMBL7158021 | 0.73 | KMT2A (0.44) | TSHRKMT2ASQLEMEN1CYP3A4 | |
| SCHEMBL234378 | 0.73 | KMT2A (0.44) | TSHRKMT2ASQLEMEN1CYP3A4 | |
| SCHEMBL11558624 | 0.73 | KMT2A (0.44) | TSHRKMT2ASQLEMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |