Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.38 |
| ▸ | MGAM | O43451 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 4/20 | 0.38 |
| ▸ | AGL | P35573 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LCT | P09848 | 2/20 | 0.36 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.36 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.36 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TREH | O43280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23802738 | 1.00 | GAA (0.38) | GAAMGAMGLAAGLSI | |
| SCHEMBL5371195 | 0.96 | — | — | |
| SCHEMBL300053 | 0.96 | — | — | |
| SCHEMBL5366493 | 0.96 | — | — | |
| SCHEMBL23058791 | 0.86 | GANAB (0.34) | GAAMGAMGLAAGLSI | |
| SCHEMBL23040228 | 0.86 | GANAB (0.34) | GAAMGAMGLAAGLSI | |
| SCHEMBL31043073 | 0.86 | GANAB (0.34) | GAAMGAMGLAAGLSI | |
| SCHEMBL6888398 | 0.84 | — | — | |
| SCHEMBL21050730 | 0.84 | — | — | |
| SCHEMBL21831505 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | claimed |
| EP-0872479-B1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO SPA (IT) | 2002-09-04 | — | — | EP | claimed |
| EP-0872479-A1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO S.p.A. (IT) | 1998-10-21 | — | — | EP | claimed |
| US-11357873-B2 | Chiral cyclen compounds and their uses | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | DCTN3, DCTN1, CDK3 | GAA 1289/4885MGAM 4299/4885GLA 3253/4885 |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | DCTN3, DCTN1, CDK3 | GAA 1289/4885MGAM 4299/4885GLA 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.