Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655495 | 0.88 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28363436 | 0.85 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18953068 | 0.81 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19668028 | 0.81 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28479741 | 0.79 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10399689 | 0.79 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL345839 | 0.78 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27982282 | 0.78 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10399536 | 0.78 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3363130 | 0.78 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653663-B1 | Organic-inorganic composite particles and production process therefor | NIPPON CATALYTIC CHEM IND (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5670257-A | HYDROLYZING AND CONDENSING ORGANOSILICON COMPOUND; HEAT TREATMENT; SPACERS FOR LIQUID CRYSTAL DISPLAY; NONFRACTURING | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5580619-A | LIQUID CRYSTAL DISPLAY | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| US-5503932-A | SPACERS FOR LIQUID CRYSTAL DISPLAYS REQUIRING UNIFORM GAP DISTANCE BETWEEN MEMBERS; RESILIENCE | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0653663-A1 | Organic-inorganic composite particles and production process therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |