Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 0.69 |
| ▸ | ACE | P12821 | 14/20 | 0.69 |
| ▸ | CPA1 | P15085 | 8/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569070 | 1.00 | MME (0.69) | MMEACECPA1ACE2 | |
| SCHEMBL7569066 | 0.93 | MME (0.67) | MMEACECPA1ACE2 | |
| SCHEMBL7569072 | 0.93 | MME (0.67) | MMEACECPA1ACE2 | |
| SCHEMBL7566353 | 0.92 | MME (0.64) | MMEACECPA1ACE2 | |
| SCHEMBL7566357 | 0.92 | MME (0.64) | MMEACECPA1ACE2 | |
| SCHEMBL8027335 | 0.90 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8027331 | 0.90 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8449859 | 0.89 | MME (0.55) | MMEACE | |
| SCHEMBL7572841 | 0.89 | MME (0.77) | MMEACECPA1ACE2 | |
| SCHEMBL7572851 | 0.89 | MME (0.77) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |