Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095556 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL5086050 | 1.00 | — | — | |
| SCHEMBL13477796 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL15787112 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7117486 | 1.00 | — | — | |
| SCHEMBL14123990 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL10278493 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL22672719 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL20628593 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL27765228 | 1.00 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079753-A2 | 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-10-10 | — | — | WO | disclosed |