Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179920 | 0.88 | KDR (1.00) | KDR | |
| SCHEMBL6179560 | 0.86 | KDR (0.78) | KDR | |
| SCHEMBL6182098 | 0.82 | KDR (0.72) | KDR | |
| SCHEMBL13701560 | 0.81 | KDR (0.81) | KDR | |
| SCHEMBL7237283 | 0.81 | KDR (1.00) | KDRCNR1 | |
| SCHEMBL6178573 | 0.81 | KDR (0.70) | KDR | |
| SCHEMBL7490947 | 0.81 | KDR (0.79) | KDR | |
| SCHEMBL7487695 | 0.80 | KDR (0.65) | KDR | |
| SCHEMBL6180047 | 0.80 | KDR (0.77) | KDR | |
| SCHEMBL6179228 | 0.79 | KDR (0.72) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218376-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-1218376-A1 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017995-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |