SCHEMBL7569348

SCHEMBL7569348

N#Cc1ccc(C(=O)O)cc1-c1cccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MCL1 Q07820 2/20 0.46
SLC22A12 Q96S37 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TTR P02766 1/20 0.44
PTPRC P08575 2/20 0.43
ACMSD Q8TDX5 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
PGGT1B P53609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16502465 0.86 SLC22A12 (0.46) XDHCYP1A2CYP2C9CYP2C19SLC22A12
SCHEMBL7916522 0.83 PLA2G2D (0.44) XDHSLC22A12
SCHEMBL7571218 0.81 CDC25B (0.50) XDHMEN1KMT2A
SCHEMBL16502582 0.80 GRIN2D (0.54) MCL1TTRPTPRCACMSDMEN1
SCHEMBL7197446 0.79 TTR (0.46) TTRPTPRCKMT2A
SCHEMBL250471 0.79 HSD17B10 (0.56) MCL1TTRPTPRCACMSDMEN1
SCHEMBL16509448 0.78 PLA2G2D (0.47) XDHCYP1A2CYP2C9CYP2C19SLC22A12
SCHEMBL28410867 0.77 MEN1 (0.52) CYP1A2CYP2C19MCL1ACMSDMEN1
SCHEMBL11937679 0.77
SCHEMBL28203557 0.76 CA1 (0.60) XDHMCL1CA1CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors ABBOTT LABORATORIES 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors FNTA, FNTB, SLC10A1 XDH 786/4885CYP1A2 276/4885CYP2C9 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.